Extraction Services

High-quality nucleic acid extraction is the foundation of reliable sequencing data. At Source Genomics, we offer a comprehensive suite of extraction and preparation services for DNA and RNA, from plasmid isolation for rapid services through to high-throughput nucleic acid extraction for NGS workflows.

Our experienced laboratory team handles every step with the rigor expected of an ISO-accredited facility, giving you confidence in your results from the first step.

Whether you need a standalone extraction service or want to pair it seamlessly with Sanger sequencing, whole plasmid nanopore sequencing, or NGS, we make it simple.

Talk to our scientists today about your genomic research needs. We provide tailored guidance and practical support to help you achieve your research goals efficiently and successfully.

DNA & RNA Extraction Services

Plasmid Extractions (part of the Rapid Sequencing Service)

Don't have time to extract your own plasmid for your Sanger sequencing or Whole Plasmid Nanopore Sequencing, then submit your overnight bacterial cultures and we'll do the extraction for you. Our high-throughput plasmid extraction service uses SPRI bead-based technology to deliver clean, sequencing-ready plasmid DNA from bacterial cultures, rapidly and at scale.

We Accept:

  • Bacterial cultures (submitted in 96-well plate format or individual tubes) - 1mL of overnight culture (grown for approx. 16 hours) or a pea-sized cell pellet.

Nucleic Acid Extractions

For NGS workflows and other applications requiring high-yield, ultra-pure DNA or RNA, our Nucleic Acid Extraction service provides an end-to-end solution. Standard extraction services produce genomic DNA or total RNA but we are also able to support high molecular weight DNA and miRNA extractions. Our scientists have processed thousands of samples and deliver consistently high-quality nucleic acids at speed in our dedicated laboratory facilities.

This service is available as a standalone offering or as part of a complete NGS project, integrating directly with our Whole Genome Sequencing, RNA-Seq, Metagenomics, Ultra Long DNA Sequencing, qPCR, STR Typing and other services.

Sample Types Accepted:

A broad range of sample types are supported. We have extracted from a range of standard sample types including Blood (whole or fractions), Saliva, Buccal Swabs, Stool, Tissue (snap frozen or preserved), FFPE, Cells (pellets, culture and supernatants) and environmental samples, as well as some more unusual materials.

Please contact us to discuss your specific material.

Key Features:

  • High yields of ultra-pure DNA and RNA
  • Suitable for a wide range of downstream applications
  • Initial QC performed on all extracted samples
  • Scalable throughput, from single-sample projects to large cohorts

Proteomics Sample Preparation

To support your proteomics work, we can help prepare your novel matrix samples. This includes sample elutions and isolations specifically for the Olink or Alamar assays.

Why Choose Source Genomics for Extractions?

  • UK-based ISO-accredited laboratory, your samples never leave the UK
  • Seamless integration, extractions can feed directly into Sanger, Nanopore, or NGS workflows in a single submission
  • Expert support, dedicated account managers and experienced scientists on every project
  • Fast turnaround, SpeedREADโ„ข delivery for Sanger-linked services; competitive turnaround for NGS extractions
  • Scalable, high-throughput capacity for both small and large-scale projects

Whether you need standalone DNA or RNA extraction or a complete workflow with sequencing, our experts are here to help. Discuss your project with our team and we'll recommend the best approach for your samples and research goals.