New NGS Services on Element Biosciences AVITI™

Source Genomics is proud to be the first UK-based commercial service provider to offer generation sequencing (NGS) using the Element Biosciences AVITI™ System.

As the demand for RNA sequencing and comprehensive DNA sequencing technology grows in the UK, we have expanded our laboratory services to meet the needs of the life science research market. This incorporation of the state-of-the-art AVITI™ System transforms based sequencing with unprecedented accuracy and cost-efficiency, providing researchers with enhanced flexibility for faster discoveries.

Exceptional quality

Our next-generation sequencing services are anchored by the advanced capabilities of Avidity Sequencing, which employs rolling circle amplification (RCA) to minimise common amplification errors. This results in exceptional sequencing quality, including:

90% reads >Q30
80% reads >Q40
70% reads >Q50 with the UltraQ workflow

Why the Element Biosciences AVITI™ System?

The Element Biosciences AVITI™ System sets new industry standards, offering:

High Accuracy and Low Error Rates: Avidity Sequencing’s RCA minimises PCR error propagation, ensuring precise sequence of DNA results.
Reduced Index Hopping: The AVITI™ platform boasts minimal index hopping, preserving the integrity of data and sample identification.
Low Duplication Rates: This system produces data with low duplication, maintaining a true representation of the original DNA fragments.
Balanced AT/GC Coverage: Achieve more uniform genome coverage with low AT/GC bias, crucial for targeted sequences and challenging genomic regions.

Key Performance Metrics

Sequencing output and run times

Read counts and quality scores

Sequencing output and run times

	2 x 75 Kit*		2 x 150 Kit*		2 x 300
Flow Cell	Output	Time*	Output	Time*	Output	Time
Low Output			75 Gb	27 hours
Medium Output	75 Gb	20 hours	150 Gb	31 hours	60 Gb	51 hours
High Output	150 Gb	24 hours	300 Gb	38 hours	180 Gb	60 hours

* Individually addressable lanes slightly extend run times.

Read counts and quality scores

	2 x 75 Kit		2 x 150 Kit		2 x 300
Flow Cell	Read Count*	Q30	Read Count	Q30	Read Count	Q30
Low Output			250 million
Medium Output	500 million	> 90%	500 million	> 90%	100 million	> 85%
High Output	1 billion	> 90%	1 billion	> 90%	300 million	> 85%

* Read counts are based on sequencing Element-prepared libraries. Actual read counts might differ based on lab-specific factors.

Comprehensive Sequencing Services

Source Genomics offers a range of sequencing services, including RNA sequencing, full-genome DNA sequencing technology, and targeted sequences for specific genomic research. We also integrate Sanger sequencing for comparative studies and validation, ensuring a comprehensive suite of options for all research needs.

The Benefits of Choosing Source Bioscience:

Pioneering UK-Based Services: Access the first commercial NGS service in the UK that utilises the AVITI™ System, a game-changer in next generation sequencing.
State-of-the-Art Technology: Our based sequencing platforms leverage cutting-edge methods to deliver high-quality results, supporting projects from clinical diagnostics to academic research.
Expert Support and Data Analysis: Our team provides full-service support, from project setup to data interpretation, enhancing the value and impact of your research.

Resources

Download the Element AVITI System Specification Sheet here.

Partner with Source Bioscience for Advanced NGS Solutions

Select Source Genomics for your next project and benefit from state-of-the-art DNA sequencing technology. Our services, powered by the Element Biosciences AVITI™ System, offer precise, cost-effective, and efficient solutions for analysing the sequence of DNA, RNA sequencing, and more. Whether you need high-throughput generation sequencing (NGS) or detailed targeted sequences, we are here to support your research journey.

Contact us today and one of our skilled account managers will be in touch with a free consultation including further information and pricing details.

Next Generation Sequencing

Whole Exome Sequencing

Whole Genome Sequencing

New Element Bio Services

Bioinformatics

Nucleic Acid Extractions

FAQs

Download Genomics Brochure

Next Generation
Sequencing

Source BioScience is one of Europe’s leading providers of commercial sequencing, offering Next Generation Sequencing services from our ISO accredited laboratories. We offer NGS services on the most prominent platforms including Illumina’s NovaSeq, NextSeq and MiSeq.

Request a quote today